https://hspsignaling.com/index.....php/difficulties-of
We find that the FMRP KH0, KH1, and KH2 domains bind weakly into the single-stranded RNA sequences suggesting which they may have developed to bind more technical RNA structures. Furthermore, we discover that the RGG theme of human FMRP binds with a top affinity to an RNAG-quadruplex structure that does not have single-stranded loops, double-stranded stems, or junctions. Multi-arm celebrity poly(ethylene glycol) (PEG) polymers have actually lots of advantages over linear PEG polymers
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