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How a VC Can Affect Your Heart Many people experience occasional PVCs and have no issues. If they are frequent, PVCs may weaken your heart and increase the risk of heart failure. The heart's rhythm is controlled by a group of nerve fibers situated in the upper right part of your heart. This is called the sinoatrial node, or SA. Electrical signals travel to the lower heart chambers or ventricles. Causes PVCs happen when the electrical impulse which normally triggers your heartbeat at the Sinus Node (also known as the Sino
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