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Rats were split into three groups (n = 10 per group) (1) intact control (no stimulation), (2) OVX control (no stimulation), and (3) OVX stimulation (treatment group). PTNS did not affect serum estradiol levels, body weight, or blood glucose. PTNS transiently increased vaginal blood perfusion during stimulation for up to 5 weeks after OVX and increased areal bone mineral density and yield load of the right femur (side of stimulation) compared to the unstimulated OVX control. PTNS may ameliorate some symptoms associated with menopause. A
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