https://www.selleckchem.com/pr....oducts/pi3k-hdac-inh
05).Hypoxic exposure for 12h also resulted in significantly lowered expression of HIF1 protein in U251 cells ( 0.05).Overexpression of MEG3 obviously suppressed the proliferation and invasiveness of U251 cells ( 0.05). MEG3 overexpression inhibits the proliferation and invasion of U251 cells through suppressing the expression of HIF1 mRNA and protein, suggesting that MEG3 may serve as a potential therapeutic target for glioblastomas. MEG3 overexpression inhibits the proliferation and invasion of U251 cells throug