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6 vs. 5.42; adjusted sHR 1.94; 95% CI, 1.53-2.46; p less then 0.001). Similarly, the 5-year incidence rate of stroke was significantly lower among chemotherapy recipients using TCM vs. non-TCM users (0.19 vs. 0.46; adjusted sHR 0.45; 95% CI, 0.26-0.79; p less then 0.001), as was the mortality rate (adjusted sHR 0.55; 95% CI, 0.44-0.68; p less then 0.001). Conclusion These Taiwanese data suggest that chemotherapy is a risk factor for stroke and that the use of TCM can significantly mitigate this risk. TCM also appears to reduce the morta