https://www.selleckchem.com/pr....oducts/sacituzumab-g
Diamond-Blackfan anemia (DBA) is a rare hematopoietic disease characterized by a block in red cell differentiation. Most DBA cases are caused by mutations in ribosomal proteins and characterized by higher than normal activity of the tumor suppressor p53. Higher p53 activity is thought to contribute to DBA phenotypes by inducing apoptosis during red blood cell differentiation. #link# Currently, there are few therapies available for patients with DBA. We performed a chemical screen using zebrafish ribosomal small subunit pro
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