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This paper introduces a new family of matrix variate distributions based on the mean-mixture of normal (MMN) models. The properties of the new matrix variate family, namely stochastic representation, moments and characteristic function, linear and quadratic forms as well as marginal and conditional distributions are investigated. Three special cases including the restricted skew-normal, exponentiated MMN and the mixed-Weibull MMN matrix variate distributions are presented and studied. Based on the specific presentation of the proposed mod