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Root-soil interactions in the rhizosphere are central to resource acquisition and crop production in agricultural systems. However, apart from studies in idealized experimental systems, rhizosphere processes in real agricultural soils in situ are largely uncharacterized. This limits the contribution of rhizosphere science to agriculture and the ongoing Green Revolution. Here, we argue that understanding plant responses to soil heterogeneity is key to understanding rhizosphere processes. We highlight rhizosphere sensing and root-induced