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An innovative method for utilizing synthetic calcium fluoride (CaF2), recovered from fluoride-containing semiconductor wastewater, and waste sulfuric acid (H2SO4) to produce hydrofluoric acid (HF) was investigated. The research was set to study the low-temperature production of HF via reaction of synthetic CaF2 and waste H2SO4. The impact of four factors, including H2SO4 concentration, total volume (H2SO4 + H2O)/CaF2 ratio, drying temperature of synthetic CaF2, and reaction carried out under different temperature, on HF productivity was