https://www.selleckchem.com/pr....oducts/CP-690550.htm
Results The results indicated that catechin molecule led to significant and dose-dependent growth inhibitory effects on U87MG human glioma cells with lower cytotoxicity in normal astrocytes. Clonogenic assay indicated strong decrease in glioma cell colonies. TEM revealed that catechin induced autophagy in U87MG cells by creating autophagosomes and autophagic vacuoles. The catechin-triggered autophagy was also linked with increase in the expression of LC3II and decrease in p62 expression. However, moderate effects were observed on the
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