https://sfrp-signal.com/index.....php/initial-investig
Here, we discovered that DNMT3A WT chemical under conditions that favor non-cooperative kinetic procedure as well as DNMT3A Arg882His variant gain CpG flanking series preference comparable to that of DNMT3B, which can be non-cooperative. We tested if DNMT3A Arg882His could preferably methylate DNMT3B-specific target internet sites in vivo. Relief experiments in Dnmt3a/3b two fold knockout mouse