https://www.selleckchem.com/pr....oducts/brefeldin-a.h
Purpose A 28-year-old male reported to our hospital with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) overlap syndrome that developed as an adverse drug reaction (ADR) to allopurinol. HLA-B*5801 allele is associated with an increased risk of developing allopurinol-induced SJS/TEN. Methods Genomic DNA was extracted from peripheral blood leukocytes. DNA sequencing was done using SANGER sequencing method. Results Pharmacogenetic testing results revealed positive for HLA-B*5801 allele. Symptoms of the patient receded af
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