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In this commentary, we evaluated the existing publications and tips regarding this dilemma. Capecitabine is an oral anticancer medicine which could trigger some side effects plus the great challenge because of its use will be make sure the medicine adherence. The purpose of this study would be to evaluate side effects and adherence to capecitabine in customers with intestinal cancer tumors. a potential research was done in a tertiary teaching hospital in Brazil. Outpatients undergoing capec