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Non-Stimulant ADHD Medication The most common prescription medication prescribed by healthcare professionals to treat ADHD is stimulants. They are used to increase the levels of chemicals called neurotransmitters within the brain. Stimulation can cause an increase in appetite, tics and heart rate fluctuations, and blood pressure. Certain adolescents and children suffer a slight slowing in growth. Guanfacine Guanfacine is a prescription drug helps people suffering from ADHD manage their behavior and focus. It is available under the brand name dr