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The extent to which online mentoring can replace classic mentoring functions has to be discussed anew.Objectives The COVID-19 pandemic caused drastic changes in medical education and might affect students' mental health and perception of study conditions. Mentoring may have mediating effects by enhancing social support. The University Medical Center Hamburg-Eppendorf (UKE) offers a voluntary general mentoring program (g-mentoring) for all interested students and a mentoring program for students with excellent course results and scientif