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Additionally, we unearthed that PD-L1 phrase in esophageal cancer cells affected the antitumor purpose of CTLs. PD-1/PD-L1 blockade could boost the certain CTL-induced lysis of HLA-A2+/MAGE-A11+ tumor cell lines addressed with 5-aza-2'-deoxycytidine. These results suggest that the treatment of cyst cells utilizing the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine augments MAGE-A11 phrase in esophageal cancer tumors cells. The mixture of epigenetic modulation by 5-aza-2'-deoxycytidi