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Genotyping of SNPs including HBG2 rs7482144, HMIP rs4895441 and rs9399137, BCL11A rs4671393 and KLF1 rs2072596 was identified. Multiple regression analyses showed that only two SNPs (HMIP rs4895441 and rs9399137) influenced Hb F levels. Interestingly, a variety of those two SNPs ended up being involving higher Hb F levels. Our study is the first to demonstrate that the rs4895441, rs9399137 of HMIP tend to be associated with elevated Hb F levels into the heterozygous β-thal 3.5 kb removal. T
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