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f psychiatric rehabilitation on SR and the potential mediating effects of changes in SR on treatment outcomes should be further investigated in longitudinal studies. Persons with multiple sclerosis (MS) and depression symptoms report real-world cognitive difficulties that may be missed by laboratory cognitive tests. To examine the relationship of depressive symptoms to cognitive monotasking versus multitasking in early MS. Persons with early MS ( = 185; ⩽5 years diagnosed) reported mood, completed monotasking and multitasking cogniti