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ADHD Medication UK For Adults The first medication that's usually prescribed is a stimulant, such as methylphenidate (Ritalin). It increases activity in parts of the brain that control attention and behavior. Adults suffering from ADHD are more likely to benefit from longer-acting formulations. They build up slowly in the bloodstream, thus avoiding the 'crash" that occurs after short-acting medications wears off. Stimulants Stimulants are the most frequently prescribed medicati