https://www.selleckchem.com/pr....oducts/epz015666.htm
HBV precore (PC) and dual basal core promoter (BCP) mutations halt and downregulate HBeAg production respectively. PC mutation is rarely associated with HBV genotype A. We sought to examine the association of these variants with HBV genotypes, age and HBeAg status in a racially diverse population in North America. Prospective study included 1036 (808 adults, 228 children) participants in the Hepatitis B Research Network. PC and BCP variants were determined by Sanger sequencing and dominant HBV species (50%) were reported. Median a
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