https://www.selleckchem.com/pr....oducts/7-12-dimethyl
During aging, muscle mass decreases, leading to sarcopenia, associated with low-level chronic inflammation (inflammaging), which induces sarcopenia by promoting proteolysis of muscle fibers and inhibiting their regeneration. Patients with a variety of pathologic conditions associated with sarcopenia, including rheumatoid arthritis (RA), have systemically elevated TNFα serum levels, and transgenic mice with TNFα over-expression (TNF-Tg mice, a model of RA) develop sarcopenia between adolescence and adulthood b
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