https://www.selleckchem.com/ALK.html
The prophage BTP1 is highly conserved among strains of the pathogenic lineage Salmonella Typhimurium (S. Typhimurium) ST313. We aimed to analyze the role of BTP1 and the gene bstA (BTP1-encoded) in virulence of S. Typhimurium D23580, the ST313 lineage 2 reference strain. The deletion mutant D23580ΔbstA showed significantly higher replication and survival rates within human derived THP-1 macrophages than the WT-strain, while the mutant strain ΔBTP1, lacking the full prophage, did not significantly differ from the WT. Interestingly, during mice infect