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Females signed up for the experimental arm of period 2 regarding the New Technologies for Cervical Cancer randomized managed cervical testing test had been tested for high-risk HPV (hrHPV) and referred to colposcopy if positive. hrHPV-positive females also had HPV genotyping (by polymerase chain effect with GP5+/GP6+ primers and reverse line blotting), immunostaining for p16 overexpression and cytology. We computed sensitivity, specificity and positive predictive value (PPV) f