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018). The hazard ratio for diabetes for an increase of 25 nmol/L in intratrial 25(OH)D level was 0.75 (95% CI 0.68-0.82) among those assigned to vitamin D and 0.90 (0.80-1.02) among those assigned to placebo. The hazard ratios for diabetes among participants treated with vitamin D who maintained intratrial 25(OH)D levels of 100-124 and ≥125 nmol/L were 0.48 (0.29-0.8 and 0.29 (0.17-0.5, respectively, compared with those who maintained a level of 50-74 nmol/L. Daily vitamin D supplementation to maintain a serum 25(OH)D level ≥100 nmol/