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Increases in ocean temperatures and in the frequency and severity of hypoxic events are expected with climate change, and may become a challenge for cultured Atlantic salmon and negatively affect their growth, immunology and welfare. Thus, we examined how an incremental temperature increase alone (Warm Normoxic-WN 12 → 20 °C; 1 °C week ), and in combination with moderate hypoxia (Warm Hypoxic-WH ~ 70% air saturation), impacted the salmon's hepatic transcriptome expr\ession compared to control fish (CT 12 °C, normoxic) using 44
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