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001), distant metastasis (p less then 0.001), and advanced TNM stage (p less then 0.001). Moreover, univariate (HR 3.98; 95% CI 1.89-11.82; p less then 0.001) and multivariate (HR 2.24; 95% CI 3.53-12.50; p less then 0.001) Cox regression analysis showed that upregulated P2X7R expression clearly correlated with worsened overall survival. In summary, our data revealed that P2X7R may serve as a reliable prognostic parameter and promising therapeutic target for gastric cancer.A rare manifestation during the post-anesthetic period may inclu