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RATIONALE A potential use of disaccharides was found in this research, as reference compounds in the kinetic method for chiral recognition and enantiomeric quantification. METHODS The experimental procedure consists of three steps (1) mixing a metal salt, an analyte and a disaccharide at a molar ratio of 122 with an analyte concentration of 20 μM; (2) introducing the mixture into an Electrospray Ionization (ESI) MS source; (3) isolating the ion [MII (ref*)2 (A)-H]+ and subjecting it to dissociation. Then through the relative ratio of tw