https://www.selleckchem.com/pr....oducts/valproic-acid
Remote ischaemic conditioning (RIC) is currently being explored as a non-invasive method to attenuate ischaemia/reperfusion injuries in organs. A randomised clinical study (CONTEXT) evaluated the effects of RIC compared to non-RIC controls in human kidney transplants. RIC was induced prior to kidney reperfusion by episodes of obstruction to arterial flow in the leg opposite the transplant using a tourniquet (4 × 5min). Although RIC did not lead to clinical improvement of transplant outcomes, we explored whether RIC induced molecul