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The absorption and fluorescence of PPA-protected Ag NDs (PPA@AgNDs) had been measured with a spectrophotometer and a spectrofluorometer, respectively. The morphology of PPA@AgNDs had been described as high-angle annular dark-field (HAADF) checking transmission electron microscopy (STEM). The biocompatibility of PPA@AgNDs ended up being examined by tetrazolium (MTT)-based assay. PolyLys-Cys-SH (series KKKKKKC) peptides had been conjugated to PPA@AgNDs via heterobifunctional crosslinkers.