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Various TB lineages were observed across the African continent, with the originally European lineage 4 spotted in all countries studied. TB molecular epidemiology tools have substantially improved our understanding of the MTBC circulating isolates, their evolution, and diversity in this highly endemic region of Africa. We found that only TB lineage 4 is present throughout all the continent and the clusters identified provides an extended insight into the disease transmission dynamics. TB molecular epidemiology tools have substantially im
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