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Embolic stroke of undetermined source (ESUS) accounts for up to 25% of strokes. Understanding risk factors associated with ESUS is important in reducing stroke burden worldwide. However, ESUS patients are younger and present with fewer traditional risk factors. Significant global variation in ESUS populations also exists making the clinical picture of this type of stroke unclear. ESUS patients were pair matched for age, sex, and ethnicity with a group of all other strokes (both = 331). Exploratory factor analysis was applied in both gr