https://www.selleckchem.com/pr....oducts/dibutyryl-cam
Objective To investigate the role of CUL4B-RING E3 ubiquitin ligase (CRL4 complex in pancreatic tumorigenesis and the molecular mechanism. Methods Pancreatic cells were divided into control group (transfected with negative control lentivirus), shCUL4B group (transfected with CUL4B lentivirus), shDDB1 group [transfected with DNA damage binding protein 1 (DDB1) lentivirus], and shCUL4B+ siSFRP1 group (transfected with CUL4B lentivirus and SFRP1-siRNA). RNA-seq was performed in pancreatic cancer cell lines with CUL4B a
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