https://www.selleckchem.com/products/gdc-0068.html
Shortly after proteasome activation we detected significantly reduced amyloid-beta load correlated with improved motor functions, reduced anxiety and frailty level. Essentially, to our knowledge this is the first report to demonstrate a dual activation of the proteasome and its downstream effects. In conclusion, these findings open up new directions for future therapeutic potential of proteasome-mediated proteolysis enhancement.The dithiocarbamate fungicide maneb (M has attracted interest due to increasing concern of the negative hea