https://www.selleckchem.com/pr....oducts/cp21r7-cp21.h
anticoagulation.OBJECTIVE Cisplatin, the most common chemotherapeutic drug for the treatment of advanced stage cervical cancers has limitations in terms of drugs resistance observed in patients partly due to functional DNA damage repair (DDR) processes in the cell. Mediator of DNA damage checkpoint 1 (MDC1) is an important protein in the Ataxia telangiectasia mutated (ATM) mediated double stranded DNA break (DS repair pathway. In this regard, we investigated the effect of MDC1 change in expression on the cisplatin sensitivity in c
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