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Nevertheless, the particular sEV components in a position to mediate aberrant results in disease cells have not been characterized. Integrins are major players in mediating sEV functions. We now have previously reported that the αVβ3 integrin is detected in sEVs of prostate cancer (PrCa) cells and transferred into receiver cells. Here, we investigate whether sEVs from αVβ3-expressing cells affect tumour development differently than sEVs from control cells that don't express αVβ3. We compared