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But, it is hard to fully expel tumors by solitary PTT, and also the outcomes of solitary dose of PTT frequency in the therapeutic upshot of PTT while the several PTT-induced resistant response in disease treatment additionally remain ambiguous. Here, water-soluble Ag2S nanoparticles (NPs) with optimal particle size (~15 nm) were synthesized and utilized as the PTT agents. The in vitro plus in vivo outcomes demonstrated that Ag2S NPs had great photothermal transformation as a result