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d some sex differences were observed. CONCLUSION Distinct life-course physical activity trajectories were identified, but there was no evidence that any of the trajectories were associated with pancreatic cancer. Future studies with larger sample sizes are needed to understand the associations between physical activity trajectories over the life-course and pancreatic cancer risk.BACKGROUND The rising number of older multimorbid in-patients has implications for medical care. There is a growing need for the identification of factors predict