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Untreated ADHD in Adults Can Lead to Feelings of Worthlessness and Depression Untreated ADHD can result in chronic underachievement and depression. This is especially the case when they don't achieve their goals in terms of personal and professional. It are difficult to establish when there are overlaps in symptoms between ADHD and depression. However, identifying the signs is the first step toward receiving treatment. 1. Feelings of inadequacy Many people who suffer from untreated ADHD