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There was no association between theIICC in normal tissue (multivariable OR per 5% increase in IICC = 1.05, 95% CI = 0.96-1.16) or in the BBD lesion (OR per 5% increase in IICC = 1.06, 95% CI = 0.96-1.18) and risk of subsequent invasive breast cancer. Also, there were no associations within subgroups defined by menopausal status, BBD histology, BMI, and history of smoking. The results of this study suggest that IICCs in BBD tissue are not associated with altered risk of subsequent invasive breast cancer. The results of this study suggest that IICCs in BBD t