https://www.selleckchem.com/pr....oducts/mitoquinone-m
A signature indicating a higher ratio of exhausted CD8+ T cells to total CD8+ T cells (ExCD8-r) was consistently associated with poorer survival, particularly among hormone receptor (HR)-positive patients. Among HR-negative patients, combinations of the absolute fraction of CD8+ T cells and ExCD8-r signature identified the CD8lowExCD8-rhigh subgroup, the most prevalent among Blacks, with the worst survival. Our findings of a distinct exhausted CD8+ T cell signature in Black breast cancer patients indicates an immunobiologic
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