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ADHD Medications For Adults Stimulants can help regulate the levels of chemical messengers that control the brain's attention. They are considered first-line medications for ADHD. Although they're not in any way habit-forming, they can trigger adverse effects like headaches and difficulty sleeping. To reduce impulsivity or hyperactivity, your doctor may prescribe guanfacine under the brand names Tenex or Intuniv (Catapres). These drugs are longer-acting than stimulants. Stimulants The most common medica