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Nonetheless, the primary results of this gene on oncogenesis through control over the PI3K-AKT-mammalian target of rapamycin (mTOR) pathway may possibly not be really the only opportunity by which PTEN affects tumour development. PTEN has been confirmed to modify the antiviral interferon community and therefore modify just how cancer cells talk to and tend to be focused by immune cells. A working, T cell-infiltrated microenvironment is crucial for immunotherapy success, that will be
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