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Despite the positive effects of Vancomycin presoaking reducing the infection rate after ACL reconstruction, the lack of prospective randomized control trials and the heterogeneity of the different studies mean it is not feasible to recommend Vancomycin presoaking of the graft universally for every ACL reconstruction patient. Cite this article EFORT Open Rev 2021;6211-216. DOI 10.1302/2058-5241.6.200059.Over the years, a number of authors have used different working definitions of instability in tuberculosis of the spine (TB s