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Adult ADHD and Comorbid Disorders Many people suffering from ADHD suffer from comorbid disorders, such as major depression (Kessler and co., 2006). Many sufferers do not respond to medications for depression and may benefit from psychotherapy. Neurotransmitters are brain chemicals that regulate and increase levels of certain brain chemicals. The most commonly prescribed stimulants are amphetamine, methylphenidate and similar medications. Medications Adults can take a variety of medications that are used for ADH