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4%) patients during a mean time of FUP 19±23 months. One-year risk of RIS was 3.4% (95%CI 1.4-6.8%). Patients with RIS were older (47.4 vs. 41.1 years, p=0.007) and more often obese (71.4 vs. 19.7%, p=0.006), and did not differ in any of other analyzed parameters and VRF. Multivariate logistic regression analysis showed obesity (OR 9.527; 95%CI 1.777-51.1) and the previous use of antiplatelets (OR 15.68; 95%CI 2.430-101.2) as predictors of recurrent IS. Despite a higher presence of VRF in young CIS patients, the risk of RIS was very low.