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Background Co-trimoxazole is an antibiotic combo utilized for the treatment of Pneumocystis jirovecii pneumonia, amongst others. Co-trimoxazole is famous to boost serum potassium. As a result, Dutch guidelines advise serum potassium monitoring in high-risk patients. Unbiased this research aimed to determine typical serum potassium increase after management of intravenous co-trimoxazole in hospitalized patients, in comparison to intravenous ceftriaxone. This research additionally aimed