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Thiotepa levels were determined making use of a stability-indicating RP-HPLC assay. In parallel, pH and osmolality had been assessed. Sub-visible particles had been counted on time 0 and 14. Thiotepa Riemser focus had been uncovered becoming stable for 14 days whenever kept at 2-8 °C, or even for 24 h when kept at 25 °C. Thiotepa concentrations in infusion solutions kept at 2-8 °C remained above 95% for the initial levels for at the least 14 days, regardless of kind of automobile option