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C57BL/6 mice were addressed with GSPE for 21 days. During the final 1 week of treatment, the mice had been administered dextran sulfate sodium (DSS) mixed in drinking water to cause experimental colitis. We unearthed that GSPE treatment enhanced DSS-induced colitis, that has been evidenced by decreases in condition activity index (DAI) results, pathological ratings, and oxidative stress and increases in zonula occludens-1 (ZO-1), occludin, and claudin-1 mRNA quantities of colon stru
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