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01). There were positive associations between levels of C-reactive protein and levels of HE4 (R= 0.631, p less then 0.001), CYFRA21-1(R= 0.431, p less then 0.001), CEA (R= 0.316, p less then 0.001), SCC (R= 0.351, p less then 0.001), CA153 (R= 0.359, p less then 0.001) and CA125 (R= 0.223, p=0.031). We concluded that elevations of serum cancer biomarkers positively correlated with the pathological progressions of COVID-19, demonstrating diffuse and acute lung injuries. This article is protected by copyright. All rights reserved. This art