https://www.selleckchem.com/pr....oducts/Staurosporine
A (11) mixture of ANXA4 and ANXA5 induces membrane rolling with a time constant intermediate between the value for the pure annexins. While binding of the pure annexins creates crystal lattices, the (11) mixture generates a random arrangement of trimers. Thus, curvature induction remains as a functional property of annexin mixtures in PMR rather than crystal formation. ANXA4 and ANXA5 colocalise at the damage site of MCF7 cells during repair. A (11) mixture of ANXA4 and ANXA5 induces membrane rolling with a time constant intermedi